Endoscopic Debridement of Post-radiation Nasopharyngeal Necrosis: The Effects of Resurfacing With a Vascularized Flap

Objectives Post-radiation nasopharyngeal necrosis (PRNN) is a serious complication that severely impacts the quality of life and survival of nasopharyngeal carcinoma patients.Endoscopic debridement is considered the first-line treatment for PRNN.This study aimed to analyze clinical outcomes, focusing on the mucosal resurfacing status and the effect

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Longitudinal kinetics of neutralizing antibodies against circulating SARS-CoV-2 variants and estimated level of group immunity of booster-vaccinated individuals during omicron-dominated COVID-19 outbreaks in the Republic of Korea, 2022

ABSTRACT The coronavirus disease 2019 pandemic persisted for 3 years and is now transitioning to endemicity.We illustrated the change in group immunity induced by vaccination (monovalent vaccines) and breakthrough infections (BIs) in a healthcare worker (HCW) cohort.Five sampling points were analyzed: before the third dose and 1, 3, 5, and 8 months

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Therapeutic Antibody-Like Immunoconjugates against Tissue Factor with the Potential to Treat Angiogenesis-Dependent as Well as Macrophage-Associated Human Diseases

Accumulating evidence suggests mega cell horse supplement that tissue factor (TF) is selectively expressed in pathological angiogenesis-dependent as well as macrophage-associated human diseases.Pathological angiogenesis, the formation of neovasculature, is involved in many clinically significant human diseases, notably cancer, age-related macular d

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